文献类型：期刊文献

英文题名：Construction of highly accessible single Co site catalyst for glucose detection

作者：Xiong, Can[1,2];Tian, Lin[2];Xiao, Chunchun[3];Xue, Zhenggang[2];Zhou, Fangyao[2];Zhou, Huang[2];Zhao, Yafei[2];Chen, Min[2];Wang, Qiuping[2];Qu, Yunteng[2];Hu, Yidong[1,2];Wang, Wenyu[2];Zhang, Yan[2];Zhou, Xiao[2];Wang, Zhiyuan[1,2];Yin, Peiqun[1,2];Mao, Yu[5];Yu, Zhen-Qiang[1];Cao, Yueqiang[4];Duan, Xuezhi[4];Zheng, Lei[5];Wu, Yuen[2]

机构：[1]Shenzhen Univ, Inst Low Dimens Mat Genome Initiat, Sch Chem & Environm Engn, Shenzhen 518060, Peoples R China;[2]Univ Sci & Technol China, Sch Chem & Mat Sci, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Peoples R China;[3]Univ Sci & Technol China, Div Life Sci & Med, Affiliated Hosp USTC 1, Hefei 230001, Peoples R China;[4]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[5]Hefei Univ Technol, Sch Food & Biol Engn, Hefei 230009, Peoples R China

年份：2020

卷号：65

期号：24

起止页码：2100

外文期刊名：SCIENCE BULLETIN

收录：;EI(收录号：20203309050499);WOS:【SCI-EXPANDED(收录号:WOS:000600068900018)】；

基金：This work was supported by the Postdoctoral Science Foundation of China (2019M653052), the Fundamental Research Funds for the Central Universities (WK2060120002), the National Key R&D Program of China (2017YFA, 0208300), and the National Natural Science Foundation of China (21671180). This fabrication of SGGT devices was performed at the USTC Center for Micro and Nanoscale Research and Fabrication. We sincerely thank the photoemission endstations beamline 1W1B station in Beijing Synchrotron Radiation Facility (BSRF), BL10B and BL11U in National Synchrotron Radiation Laboratory (NSRL) in Hefei, China.

语种：英文

外文关键词：Glucose sensor; Sensitivity; Selectivity; Single site catalyst; Solution-gated graphene transistor

摘要：The development of high-performance glucose sensors is an urgent need, especially for diabetes mellitus diagnosis. However, the glucose monitoring is conventionally operated in an invasive finger-prick manner and their noninvasive alternatives largely suffered from the relatively poor sensitivity, selectivity, and stability, resulted from the lack of robust and efficient catalysts. In this paper, we design a concave shaped nitrogen-doped carbon framework embellished with single Co site catalyst (Co SSC) by selectively controlling the etching rate on different facet of carbon substrate, which is beneficial to the diffusion and contact of analyte. The Co SSC prompts a significant improvement in the sensitivity of the solution gated graphene transistor (SGGT) devices, with three orders of magnitude better than those of SGGT devices without catalysts. Our findings expand the field of single site catalyst in the application of biosensors, diabetes diagnostics and personalized health-care monitoring. (c) 2020 Science China Press. Published by Elsevier B.V. and Science China Press. All rights reserved.