文献类型：期刊文献

英文题名：Ghanamycins A and B, two novel γ-butyrolactones from marine-derived streptomyces ghanaensis TXC6-16

作者：Xu, Jia-hui[1];Gu, Kang-bo[1];Zhang, Dao-Jing[1];Li, Yuan-Guang[1];Tian, Li[2]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]State Ocean Adm, Inst Oceanog 1, Qingdao, Peoples R China

年份：2017

卷号：70

期号：6

起止页码：733

外文期刊名：JOURNAL OF ANTIBIOTICS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000402447800003)】；

基金：This work was financially supported by the High-Tech Program (863 Program) of China (2008AA09Z407), National Natural Science Foundation of China No. 40776098 and 40976104, and the National Special Fund for State Key Laboratory of Bioreactor Engineering, Grant No 2060204.

语种：英文

摘要：Two novel gamma-butyrolactones ghanamycins A (1) and B (2) were isolated from the fermentation broth of marine-derived Streptomyces ghanaensis TXC6-16. Their structures were elucidated by spectroscopic analysis. These two novel compounds exhibited antimicrobial activities against some phytopathogens. The minimum IC (MIC) of 2 against Pseudomonas syringae and Erwinia sp. were 50 mu g mI(-1).