文献类型：期刊文献

英文题名：Spatiotemporal control over self-assembly of supramolecular hydrogels through reaction-diffusion

作者：Wang, Hucheng[1];Wang, Kainan[3];Bai, Shengyu[1];Wei, Lai[1];Gao, Yuliang[1];Zhi, Kangkang[2];Guo, Xuhong[1];Wang, Yiming[1,4]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]Naval Med Univ, Affiliated Hosp 2, Dept Vasc Surg, Shanghai 200003, Peoples R China;[3]Univ Shanghai Sci & Technol, Sch Hlth Sci & Engn, Shanghai 200093, Peoples R China;[4]East China Univ Sci & Technol, Shanghai Key Lab Intelligent Sensing & Detect Tech, Shanghai 200237, Peoples R China

年份：2024

卷号：664

起止页码：938

外文期刊名：JOURNAL OF COLLOID AND INTERFACE SCIENCE

收录：;EI(收录号：20241215788043);WOS:【SCI-EXPANDED(收录号:WOS:001225823500001)】；

基金：We acknowledge the financial support of Shanghai Pilot Program for Basic Research (22TQ1400100-9) , the "Chenguang Program" supported by the Shanghai Education Development Foundation and Shanghai Municipal Education Commission (20CG36) , National Key Research and Development Program of China (2022YFD70050101) , Natural Science Foundation of Shanghai (22ZR1417700) , the Open Project of State Key Laboratory of Chemical Engineering (SKL-ChE-23C01) , Natural Science Foundation of China (81971710) , and Biomedical Science and Technology Supporting Special Project, Shanghai Science and Technology Innovation Action Plan (20S31902000) .

语种：英文

外文关键词：Hydrogels; Supramolecular chemistry; Colloidal materials; Non-equilibrium system; Reaction -diffusion

摘要：Supramolecular self-assembly is ubiquitous in living system and is usually controlled to proceed in time and space through sophisticated reaction-diffusion processes, underpinning various vital cellular functions. In this contribution, we demonstrate how spatiotemporal self-assembly of supramolecular hydrogels can be realized through a simple reaction-diffusion-mediated transient transduction of pH signal. In the reaction-diffusion system, a relatively faster diffusion of acid followed by delayed enzymatic production and diffusion of base from the opposite site enables a transient transduction of pH signal in the substrate. By coupling such reaction-diffusion system with pH-sensitive gelators, dynamic supramolecular hydrogels with tunable lifetimes are formed at defined locations. The hydrogel fibers show interesting dynamic growing behaviors under the regulation of transient pH signal, reminiscent of their biological counterpart. We further demonstrate a proof-ofconcept application of the developed methodology for dynamic information encoding in a soft substrate. We envision that this work may provide a potent approach to enable transient transduction of various chemical signals for the construction of new colloidal materials with the capability to evolve their structures and functionalities in time and space.