文献类型：期刊文献

英文题名：Direct process integration of extraction and expanded bed adsorption in the recovery of crocetin derivatives from Fructus Gardenia

作者：Zhang, Min[1,3]; Hu, Ping[2]; Liang, Qionglin[3]; Yang, Huihua[3]; Liu, Qingfei[4]; Wang, Yiming[3]; Luo, Guoan[1,3]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Pharm, Modern Engn Ctr Tradit Chinese Med, Shanghai 200237, Peoples R China;[3]Tsinghua Univ, Sch Med, Res Ctr Modernizat Tradit Chines Med, Beijing 100084, Peoples R China;[4]Tsinghua Univ, Dept Chem, Beijing 100084, Peoples R China

年份：2007

卷号：858

期号：1-2

起止页码：220

外文期刊名：JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

收录：;EI(收录号：20074110855307);WOS:【SCI-EXPANDED(收录号:WOS:000250608200028)】；

语种：英文

外文关键词：crocetin derivatives; fructus gardenia; process integration; expanded bed adsorption

摘要：A process that integrated an extraction tank (EXT) and an expanded bed adsorption (EBA) into a new system EXT-EBA for direct purifying crocetin derivatives from Fructus Gardenia was described. Conditions were set to allow the extraction and purification in a single step. A comparison between the integrated process and the conventional process to purify crocetin derivatives was presented. The integrated process resulted in 52.79% recovery of crocin compared to 24.12% in the conventional process. The process time and solvent used were decreased in the integrated process. The result suggests that the EXT-EBA integrates extraction, clarification, and purification in a single step, greatly simplifying the process flow and reducing the cost and time of extraction and purification of crocetin derivatives from Fructus Gardenia. (C) 2007 Elsevier B.V. All rights reserved.