文献类型：期刊文献

英文题名：A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

作者：Chen, Xiani[1];Xu, Hang[1];Ma, Shengnan[1];Tong, Hongjuan[1,2];Lou, Kaiyan[1];Wang, Wei[1,3]

机构：[1]East China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Shanghai Key Lab Chem Biol, Sch Pharm,State Key Lab Bioengn Reactor, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Shaanxi Inst Int Trade & Commerce, Sch Pharm, Xian 712046, Shaanxi, Peoples R China;[3]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2018

卷号：8

期号：24

起止页码：13388

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20181605034763);WOS:【SCI-EXPANDED(收录号:WOS:000430018700040)】；

基金：This work was supported by the National Natural Science Foundation of China (Grant No. 21577037, K. L.) and the East China University of Science and Technology (start-up funds, W. W.).

语种：英文

外文关键词：Photons - Lanthanum compounds - Amino acids - Fluorescence - Infrared devices - Infrared lasers

摘要：Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.