文献类型：期刊文献

英文题名：Identification of prenyl flavonoid glycosides and phenolic acids in Epimedium koreanum Nakai by Q-TOF-MS combined with selective enrichment on "click oligo (ethylene glycol)" column

作者：Wang, Yaqin[1,2];Guo, Zhimou[1];Jin, Yu[3];Zhang, Xiuli[1];Wang, Li[1];Xue, Xingya[1];Liang, Xinmiao[1]

机构：[1]Chinese Acad Sci, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China;[2]Shenyang Ligong Univ, Sch Environm & Chem Engn, Shenyang 110168, Peoples R China;[3]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

年份：2010

卷号：51

期号：3

起止页码：606

外文期刊名：JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000272025800015)】；

基金：This work was supported by "Programs Funded by Ministry of Science & Technology of China During the 11th Five-year Plan (2006BA106A01-06)", "Project of International Cooperation Plan from Ministry of Science and Technology of China (2007DFC30550)".

语种：英文

外文关键词：Q-TOF-MS; Prenyl flavonoid glycosides; Phenolic acids; Selective enrichment; "Click oligo (ethylene glycol)"; Epimedium koreanum Nakai

摘要：Prenyl flavonoid glycosides and phenolic acids are constituents of the medicinal plant Epimedium koreanum Nakai (EK). An efficient method was developed to enrich these compounds and identify them, using ultra performance liquid chromatography combined with Q-TOF-MS, and a "click oligo (ethylene glycol)" (Click OEG) column. Using this method, 51 prenyl flavonoid glycosides and 18 phenolic acids were identified or tentatively identified. Of these, 11 prenyl flavonoid glycosides and 4 phenolic acids were new compounds, and 7 phenolic acids were newly identified in EK. Therefore, MS combined with selective enrichment provided a powerful means for analyzing prenyl flavonoid glycosides and phenolic acids. (C) 2009 Elsevier B.V. All rights reserved.