文献类型：期刊文献

英文题名：Influence of microwave irradiation on DNA hybridization and polymerase reactions

作者：Sun, Jinyu[1,2];Vanloon, Jesse[1];Yan, Hongbin[1]

机构：[1]Brock Univ, Dept Chem, 1872 Sir Isaac Brock Way, St Catharines, ON L2S 3A1, Canada;[2]East China Univ Sci & Technol, Sch Mat Sci & Engn, Meilong Rd 130, Shanghai 200237, Peoples R China

年份：2019

卷号：60

期号：39

外文期刊名：TETRAHEDRON LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000491304300004)】；

基金：The authors thank Natural Science and Engineering Research Council of Canada for funding this work. One of us (JS) thanks a fellowship from the Chinese Scholarship Council (201806745035).

语种：英文

外文关键词：Microwave irradiation; DNA hybridization; FRET; Polymerase chain reaction

摘要：We report herein that exposure of DNA to microwave irradiation at constant temperature leads to faster strand exchange, as compared with same experiments carried out in a water bath at the same temperature. Furthermore, polymerase chain reactions carried out under microwave irradiation were faster than those in a water bath at the same temperature as well. While the causes of these differences are unclear at this time, this research suggests that microwave irradiation can lead to subtle changes in DNA structural dynamics and functions. (C) 2019 Elsevier Ltd. All rights reserved.