文献类型：期刊文献

英文题名：One-Pot, Three-Component Reaction Using Modified Julia Reagents: A Facile Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles in a Wet Organic Solvent

作者：Chai, Huihui[1];Guo, Ruiqiang[1];Yin, Wei[1];Cheng, Lingping[1];Liu, Renhua[1];Chu, Changhu[1]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab New Drug Design, Sch Pharm, Shanghai 200237, Peoples R China

年份：2015

卷号：17

期号：3

起止页码：147

外文期刊名：ACS COMBINATORIAL SCIENCE

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000350841000001)，CCR-EXPANDED(收录号:WOS:000350841000001)】；

基金：We acknowledge the financial support from the National Natural Science Foundation of China (No. 21172072, No. 21372081).

语种：英文

外文关键词：multicomponent reaction; Julia reagent; 1,2,3,-triazoles; sodium azide; one pot

摘要：A new one-pot, three component reaction involving the use of Julia reagent, aldehyde, and sodium azide was developed for the efficient synthesis of N-unsubstituted 1,2,3-triazoles. This reaction could be carried out under mild reaction conditions without any precaution, and broad scope of substrates, both respect to Julia reagents and aldehydes, could be applied in this reaction system in generation of a small library of title compounds.