文献类型：期刊文献

中文题名：固体超强酸TiO_2/SO_4^(2-)催化合成水杨酸异戊酯工艺过程研究

英文题名：A TECHNOLGY FOR SYNTHESIS OF ISOAMYL SALICYLATE BY USING THE TiO_2/SO_4^( 2-) AS CATALYST

作者：施云海[1];方波[1];徐志国[1]

机构：[1]华东理工大学化学工程研究所,上海200237

年份：2001

卷号：9

期号：6

起止页码：19

中文期刊名：化工科技

外文期刊名：Science & Technology in Chemical Industry

收录：CSTPCD

基金：上海市化学试剂公司委托开发项目。

语种：中文

中文关键词：固体TiO2/SO4^2-催化剂;水杨酸异戊酯;异戊醇;水杨酸;反应动力学;固体超强酸

外文关键词：Solid TiO 2/SO 4 2- catalysis;Isoamyl salicylate;Isomayl alcohol;Salicylic acid;Reaction kinetics

摘要：以异戊醇和水杨酸为原料 ,以化学纯的硫酸钛为催化剂合成水杨酸异戊酯 ,研究了醇酸比、催化剂用量、反应时间和带水剂用量等对反应转化率的影响 ,以及反应产物的精馏分离条件。同时根据非等温变体积条件下动态液固相反应的特点 ,建立了合成过程的宏观动力学方程。结果表明 :在醇酸摩尔比 2 .5、反应温度 1 2 5～ 1 32℃、催化剂和带水剂用量均为反应物质量的 3%、反应 8小时条件下 ,水杨酸的转化率可达 99.3%以上 ,收率达 92 %以上。该酯化反应服从二级动力学模型 ,宏观活化能为7.94 74× 1 0 4 J/mol,频率因子为 1 .4 76 3× 1 0 9L/mol·h。
Isoamyl salicylate was prepared by esterification of salicylic acid with isoamyl alcohol using titanium sulfate in chemical purity grade. The effects of molar ratio of isoamyl alcohol to salicylic acid, the amount of catalysis and the water carrying agent and reaction time on the conversion, and also the operation conditions of distillation tower, were studied. Based on the dynamic character of non-isothermal and variable voluminal liquid solid reactions, the macro kinetics equation was established. The results showed that the optimum conditions were molar ratio of alcohol to acid being 2.54, weight of catalyst and water carrying agent both being 3%wt., reaction time being 8 hours. On these conditions, the conversion of salicylic acid was greater than 99.3%, and the yield of isoamyl salicylate was greater than 92%. The esterification was consistent in secondary dynamic model, and the macro kinetic activiation energy 7.9474×10 4 and frequency factor 1.4763×10 9/mol·h.