文献类型：期刊文献

英文题名：Effects of interrupting prolonged sitting on postprandial glycemia and insulin responses: A network meta-analysis

作者：Quan, Minghui[1];Xun, Pengcheng[2];Wu, Hua[3];Wang, Jing[4];Cheng, Wei[5];Cao, Meng[6];Zhou, Tang[1];Huang, Tao[7];Gao, Zan[8];Chen, Peijie[1]

机构：[1]Shanghai Univ Sport, Sch Kinesiol, Shanghai 200438, Peoples R China;[2]Indiana Univ, Sch Publ Hlth Bloomington, Dept Epidemiol & Biostat, Bloomington, IN 47405 USA;[3]Jiazing Univ, Rehabil Med Ctr, Affiliated Hosp 2, Jiaxing 314000, Peoples R China;[4]East China Univ Sci & Technol, Sch Sports Sci & Engn, Shanghai 200237, Peoples R China;[5]Tongji Univ, Dept Endocrinol, Yangpu Hosp, Shanghai 200090, Peoples R China;[6]Shenzhen Univ, Normal Coll, Inst Phys Educ, Shenzhen 518061, Peoples R China;[7]Shanghai Jiao Tong Univ, Dept Phys Educ, Shanghai 200240, Peoples R China;[8]Univ Minnesota, Sch Kinesiol, Minneapolis, MN 55455 USA

年份：2021

卷号：10

期号：4

起止页码：419

外文期刊名：JOURNAL OF SPORT AND HEALTH SCIENCE

收录：;WOS:【SSCI(收录号:WOS:000677513900004)，SCI-EXPANDED(收录号:WOS:000677513900004)】；

基金：The authors thank Dr Shi Qu, from the Institute of Urology, West China Hospital of Sichuan University, for his advice on data analysis. This work was supported by grants to MQ from the National Key Research and Development Program of China (2020YFC2003301 and 2020YFC2007005), National Natural Science Foundation of China (81703252), and Shanghai Committee of Science and Technology of China (19080503000); and to HW from the Public Welfare Technology Project of the Zhejiang Science Department (LGF18H170006).

语种：英文

外文关键词：Glucose; Insulin; Physical activity interruption; Prolonged sitting; Meta-analytic review

摘要：Purpose: This study aimed to evaluate the effectiveness of physical activity (PA) interrupting prolonged sitting (PS) on postprandial glycemia and insulin responses among adults. Methods: PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL, PsycINFO, and the China National Knowledge Infrastructure databases were searched through September 30, 2020. Randomized controlled trials (RCTs) that examined the effect of all forms of PA interrupting PS on postprandial glycemia and/or insulin responses among adults without chronic diseases were included in this study. The risk of bias of included studies was evaluated based on the Cochrane tool. A network meta-analysis was performed to estimate the summary standardized mean differences (SMDs) with 95% confidence intervals (95%CIs) with random effects. Results: Thirty crossover RCTs were included in our review. These RCTs included 9 types of interventions that interrupted PS. When compared to PS by itself, light-intensity PA intermittent interrupting (LPA-INT) PS and moderate-intensity PA intermittent interrupting (MPA-INT) PS significantly lowered postprandial glycemia (SMD = -0.46, 95%CI: -0.70 to -0.21; SMD = -0.69, 95%CI: - 1.00 to -0.37, respectively) and significantly reduced postprandial insulin response (SMD = -0.46, 95%CI: -0.66 to - 0.26; SMD =-0.47, 95%CI: -0.77 to -0.17, respectively). Results of the clustered ranking plot indicated that MPA-INT was the most effective intervention in lowering postprandial glycemia and insulin responses. Conclusion: Replacing PS with MPA-INT or LPA-INT has a positive effect in reducing postprandial glycemia and insulin responses, with MPA-INT being the optimal intervention strategy.