文献类型：期刊文献

英文题名：Identification of priority pharmaceuticals in the water environment of China

作者：Sui, Qian[1,2];Wang, Bin[2];Zhao, Wentao[3];Huang, Jun[2];Yu, Gang[2];Deng, Shubo[2];Qiu, Zhaofu[1];Lu, Shuguang[1]

机构：[1]E China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[2]Tsinghua Univ, THU VEOLIA Joint Res Ctr Adv Environm Technol, Sch Environm, Beijing 100084, Peoples R China;[3]Tongji Univ, State Key Lab Pollut Control & Resource Reuse, Shanghai 200092, Peoples R China

年份：2012

卷号：89

期号：3

起止页码：280

外文期刊名：CHEMOSPHERE

收录：;EI(收录号：20123015278660);WOS:【SCI-EXPANDED(收录号:WOS:000307681600012)】；

基金：This work was partly supported by China Postdoctoral Science Foundation (No. 2011M500071), the Foundation of The State Key Laboratory of Pollution Control and Resource Reuse, China (No. PCRRG 11017), the Foundation of State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (No. MARC2011D032), and Special Fund of State Key Joint Laboratory of Environment Simulation and Pollution Control (No. 11K10ESPCT).

语种：英文

外文关键词：Pharmaceutical; Priority; Ranking; Consumption; Wastewater; Ecological effect

摘要：In recent years, increasing attention has been paid to the trace-level contamination of pharmaceuticals in the water environment all over the world. Considering a large number of pharmaceuticals used, it is crucial to establish a priority list of pharmaceuticals that should be monitored and/or treated first. In the present study, we developed a ranking system based on the pharmaceutical consumption, removal performance in the wastewater treatment plants (WWTPs) and potential ecological effects, and applied to the situation of China. 39 pharmaceuticals, which had available consumption data and also been reported previously in the WWTPs of China, were selected as candidate pharmaceuticals. Among them, seventeen pharmaceuticals were considered as priority pharmaceuticals, out of which, erythromycin, diclofenac acid and ibuprofen, had the high priority. Compared with other literatures, we found that some pharmaceuticals given concerns to globally should also be included in the priority list in China: while some pharmaceuticals, not mentioned in other literatures, such as cefalexin, ketoconazole, should be also given prior consideration in China. Among all the therapeutic classes, antibiotics, which were grossly abused in China, contributed the most to the priority pharmaceuticals. However, priority antibiotics accounted for only 32% of candidate antibiotics, while 71% and 100% of the candidate anti-inflammatory and anti-lipidemic respectively were identified as the priority pharmaceuticals, indicating that antibiotics might be overanxiously considered in the previous studies on their behaviors in the WWTPs of China. (C) 2012 Elsevier Ltd. All rights reserved.