文献类型：期刊文献

英文题名：Oxazolonaphthalimides and their hydroperoxides: photophysical and photobiological properties

作者：Yao, Wei[1]; Qian, Xuhong[2]

机构：[1]E China Univ Sci & Technol, Inst Pesticides & Pharmaceut, Shanghai 200237, Peoples R China;[2]Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China

年份：2001

卷号：48

期号：1

起止页码：43

外文期刊名：DYES AND PIGMENTS

收录：;EI(收录号：2001055454050);WOS:【SCI-EXPANDED(收录号:WOS:000166383500006)】；

语种：英文

外文关键词：oxazolonaphthalimide; hydroperoxide; DNA photocleave; plazmid nicking

摘要：Novel oxazolonaphthalimide hydroperoxides 2 and 3 have been designed, synthesized and shown to be very efficient in photocleavage of DNA by the plazmid nicking assay. The absorption and fluorescence properties of these compounds and their relevant intermediates are discussed. An explanation for the higher DNA-cleavage efficiency of these oxazole-conjugated naphthalimide hydroperoxides than the nonsubstituted counterpart 1 is provided. (C) 2001 Elsevier Science Ltd. All rights reserved.