文献类型：期刊文献

英文题名：Double carbometallation of alkynes: an efficient strategy for the construction of polycycles

作者：Luo, Yong[1];Pan, Xiaolin[1];Yu, Xingxin[2];Wu, Jie[1,3]

机构：[1]Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China;[2]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

年份：2014

卷号：43

期号：3

起止页码：834

外文期刊名：CHEMICAL SOCIETY REVIEWS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000329927100007)】；

语种：英文

摘要：Cyclization reactions of alkynes, especially the double carbometallation of alkynes, have drawn much interest from organic chemists because of their high efficiency in the construction of polycycles. Utilizing different nucleophiles or catalytic systems, various efficient strategies to access challenging skeletons have been extensively explored in recent years. In this review, achievements in this field are presented in three major parts (the syn-syn, anti-anti, and syn-anti addition reactions of diynes or two alkyne molecules). Cyclization reactions of diynes initiated by nucleophiles, [2+2+n] cycloaddition, or other processes and reactions, involving two identical or different alkynes are described, which provide facile and reliable approaches to various p systems, medium-sized rings, and even macrocycles.