文献类型：期刊文献

中文题名：通过η~3-苄基钯中间体零价钯催化的吲哚苄基化反应(英文)

英文题名：Pd(0)-catalyzed benzylation of indole through η~3-benzyl palladium intermediate

作者：赵正乐[1,2];顾庆[2];伍新燕[1];游书力[1,2]

机构：[1]华东理工大学结构可控先进功能材料及其制备教育部重点实验室和精细化工研究所,上海200237;[2]中国科学院上海有机化学研究所金属有机国家重点实验室,上海200032

年份：2015

卷号：36

期号：1

起止页码：15

中文期刊名：催化学报

外文期刊名：CHINESE JOURNAL OF CATALYSIS

收录：CSTPCD;;EI(收录号：20153801286930);Scopus;WOS:【SCI-EXPANDED(收录号:WOS:000348274200004)】；北大核心:【北大核心2014】；CSCD:【CSCD2015_2016】；

基金：This work was supported by the National Basic Research Program of China (973 Program, 2010CB833300) and the National Natural Science Foundation of China (21025209, 21121062, 21272253, 21332009).

语种：中文

中文关键词：苄基化;吲哚;三芳基甲烷;η3-苄基钯中间体

外文关键词：Benzylation; Indole; Triarylmethane; η3‐Benzyl palladium intermediate

摘要：本文报道了零价钯催化的吲哚苄基化反应,获得了优秀的区域选择性.使用Pd(PPh3)4作为催化剂,在温和反应条件下,以90%–99%的收率获得含有各类取代吲哚片段的三芳基甲烷化合物.
An efficient method has been developed for the Pd（0）-catalyzed benzylation of indoles, which oc-curred with exclusive regioselectivity. When this reaction was performed in the presence of Pd（PPh3）4, it provided access to a broad range of substituted indoles bearing diarylmethanes at their 3-position in 90%–99% yields under mild conditions.