文献类型：期刊文献

英文题名：Dihydro-Si-rhodamine for live-cell localization microscopy

作者：Zhang, Xiaodong[1];Zhang, Mengmeng[1];Yan, Yu[2];Wang, Mingkang[1];Li, Jin[1];Yu, Yang[1];Xiao, Yi[2];Luo, Xiao[3];Qian, Xuhong[1];Yang, Youjun[1]

机构：[1]East China Univ Sci & Technol, Sch Pharm, State Key Lab Bioreactor Engn, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[2]Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China;[3]East China Normal Univ, Sch Chem & Mol Engn, Shanghai 200241, Peoples R China

年份：2021

卷号：57

期号：61

起止页码：7553

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;EI(收录号：20213110716153);WOS:【SCI-EXPANDED(收录号:WOS:000671299500001)】；

基金：This work was supported by the National Natural Science Foundation of China (No. 21822805, 21908065 and 22078098), China Post-doctoral Science Foundation (No. 2019M651427, and 2020T130197), and the Commission of Science and Technology of Shanghai Municipality (18430711000).

语种：英文

外文关键词：Silicon - Fluorophores

摘要：Fluorophores with photo-modulatory fluorescence properties are valuable for cutting-edge localization microscopy. The existing probes are either photo-activatable, or photo-switchable, but not both. We report a probe (DH-SiR), a leuco-dye obtained by reduction of Si-rhodamine, with both photo-activatable and photo-switchable fluorescence. The potential for super-resolution microscopy was showcased.