文献类型：期刊文献

英文题名：Antimicrobial Properties and Application of Polysaccharides and Their Derivatives

作者：Xia, Gui-Xue[1];Wu, Yue-Ming[2];Bi, Yu-Fang[2];Chen, Kang[2];Zhang, Wei-Wei[2];Liu, Shi-Qi[2];Zhang, Wen-Jing[2];Liu, Run-Hui[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Frontiers Sci Ctr Mat & Dynam Chem, Key Lab Specially Funct Polymer Mat & Related Tec, Minist Educ,Sch Mat Sci & Engn, Shanghai 200237, Peoples R China

年份：2021

卷号：39

期号：2

起止页码：133

外文期刊名：CHINESE JOURNAL OF POLYMER SCIENCE

收录：;EI(收录号：20212810632837);WOS:【SCI-EXPANDED(收录号:WOS:000580496500001)】；

基金：This work was financially supported by the Natural Science Foundation of Shanghai (No. 18ZR1410300), the National Natural Science Foundation of China (Nos. 21861162010, 21774031, and 31800801), the National Key Research and Development Program of China (No. 2016YFC1100401), and Research program of State Key Laboratory of Bioreactor Engineering, the Fundamental Research Funds for the Central Universities (Nos. 22221818014 and 50321041917001).

语种：英文

外文关键词：Antimicrobial; Drug resistance; Polysaccharides; Polysaccharide derivatives; Chitosan

摘要：With the quick emergence of antibiotic resistance and multi-drug resistant microbes, more and more attention has been paid to the development of new antimicrobial agents that have potential to take the challenge. Polysaccharides, as one of the major classes of biopolymers, were explored for their antimicrobial properties and applications, owing to their easy accessibility, biocompatibility and easy modification. Polysaccharides and their derivatives have variable demonstrations and applications as antimicrobial agents and antimicrobial biomaterials. A variety of polysaccharides, such as chitosan, dextran, hyaluronic acid, cellulose, other plant/animal-derived polysaccharides and their derivatives have been explored for antimicrobial applications. We expect that this review can summarize the important progress of this field and inspire new concepts, which will contribute to the development of novel antimicrobial agents in combating antibiotic resistance and drug-resistant antimicrobial infections.