文献类型：专利

英文题名：New polyethylene glycol block polypeptide molecular brush used for preparing hydrogel, comprises diblock polymer comprising polyethylene glycol and polypeptide as main chain, and alkoxy ether dendrimer as side chain

作者：CHEN Y;HU C;HE X;LIN X;LIN S;ZHU H

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY;[2]UNIV EAST CHINA NORMAL;[3]UNIV EAST CHINA SCI & TECHNOLOGY

申请号：CN104592511-A

申请日：2015-01-19

公开日：2015-05-06

语种：英文

收录：DERWENT

摘要：NOVELTY - A polyethylene glycol block polypeptide molecular brush (I) comprising diblock polymer comprising polyethylene glycol and polypeptide as main chain, and alkoxy ether dendrimer as side chain, is new. USE - New polyethylene glycol block polypeptide molecular brush is used for preparing hydrogel for drug loading applications (all claimed), functional material, cell culture medias and medicine carrier. ADVANTAGE - The hydrogel obtained using the polyethylene glycol block polypeptide molecular brush has unique structure and morphology, and excellent biocompatibility. DETAILED DESCRIPTION - A polyethylene glycol block polypeptide molecular brush of formula (I) comprising diblock polymer comprising polyethylene glycol and polypeptide as main chain, and alkoxy ether dendrimer as side chain, is new. n=30-100;and X=methyl or ethyl. INDEPENDENT CLAIMS are included for the following: (1) preparation of polyethylene glycol block polypeptide molecular brush (I); (2) hydrogel, which comprises ( alpha )-cyclodextrin and polyethylene glycol block polypeptide molecular brush (I); and (3) preparation of hydrogel, which involves dissolving polyethylene glycol block polypeptide molecular brush in water, adding ( alpha )-cyclodextrin, ultrasonically treating, and leaving-still.