文献类型：期刊文献

英文题名：Efficient synthesis and insecticidal activity of novel pyridin-3-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles

作者：Qian, Qun[1];Zhu, Yiwen[1];Zhang, Min[1];Lu, Dongliang[1];Cao, Weiguo[2];Song, Liping[2];Huang, Qingchun[3]

机构：[1]Shanghai Univ, Coll Sci, Dept Chem, Shanghai 200444, Peoples R China;[2]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China;[3]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2013

卷号：144

期号：2

起止页码：231

外文期刊名：MONATSHEFTE FUR CHEMIE

收录：;EI(收录号：20242616521247);WOS:【SCI-EXPANDED(收录号:WOS:000314333900018)】；

基金：This work was supported by the National Natural Science Foundation of China (NNSFC) (nos 21072128, 20772080), the Leading Academic Discipline Project of Shanghai Municipal Education Commission (no. J50102), the Foundation of Education Commission of Shanghai Municipality (08zz44), and the Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry.

语种：英文

外文关键词：Pyridine; [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazoles; Bioactivity

摘要：A series of novel [1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles bearing pyridine ring derivatives was synthesized from 2,6-dimethylpyridin-3,5-dicarboxylic acid diethyl ester. The structures of the compounds were characterized by use of IR, NMR, EI-MS, and elemental analysis. The structure of one compound was further confirmed by X-ray diffraction analysis. Biological assays showed that these compounds had potential insecticidal activity with especially strong regulation of the growth of 2nd instar Mythimna separata larvae. The effects on bioactivity of substituent groups on phenyl ring were also screened. .