文献类型：期刊文献

英文题名：Engineering the outermost surface of mesoporous carbon beads towards the broad-spectrum blood-cleansing application

作者：Chen, Mingqi[1];Pan, Min[1];Chong, Yanping[1];Wang, Jitong[1];Long, Donghui[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Shanghai Key Lab Multiphase Mat Chem Engn, Shanghai 200237, Peoples R China

年份：2018

卷号：130

起止页码：782

外文期刊名：CARBON

收录：;EI(收录号：20180704781890);WOS:【SCI-EXPANDED(收录号:WOS:000424889200092)】；

基金：This work was partly supported by MOST (2014CB239702) and National Science Foundation of China (No. 21576090), and Fundamental Research Funds for the Central Universities (222201718002).

语种：英文

外文关键词：Blood - Mesoporous materials - Surface structure - Suspensions (fluids) - Carbon

摘要：The properties of the outermost surfaces of porous carbons are critical in determining their functions especially for the accessibility of adsorbate into the bulk pores. Herein, a concept that engineering the outermost surface of mesoporous carbons to improve their function and serviceability is provided. By using a suspension-assisted colloidal silica templating, millimeter-sized mesoporous carbon beads (MCBs) are prepared, which not only possess very developed mesoporous structure, but also have a macroscopically spherical form with a nanostructured outermost surface layer. It is realized that such surface layer could dramatically improve the holistic properties of MCBs including mechanical strength, liquidity and wear resistant. Such surface layer could also efficiently suppress platelet adhesion/activation and avoid blood hemolysis and clotting, allowing the MCBs directly contact with blood. Moreover, the surface layer with mesopores could serve as a selective filtering membrane accessible for the small and middle toxins, guaranteeing the broad-spectrum blood cleansing application. This work reveals the surface structure of porous carbons that is distinct from the bulk, and its understanding and control should be of great importance both from fundamental and practical points of view. (c) 2018 Elsevier Ltd. All rights reserved.