文献类型：期刊文献

英文题名：Highly structured solvents enable integrated organogel networks with robust adhesion and mechanics

作者：Sha, Dongyong[1,2,5];Zha, Yang[1,3];Ding, Ding[1,2];Tang, Shuaimin[1,2];Zhang, Jianxing[4];Ling, Xiaofeng[4];Liu, Changsheng[1,2];Gao, Liang[1,3];Yuan, Yuan[1,2]

机构：[1]East China Univ Sci & Technol, Frontiers Sci Ctr Materiobiol & Dynam Chem Engn, Sch Mat Sci & Engn, Key Lab Ultrafine Mat,Minist Educ, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Res Ctr Biomed Mat, Sch Mat Sci & Engn, Minist Educ, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Shanghai Key Lab Adv Polymer Mat, Shanghai 200237, Peoples R China;[4]East China Univ Sci & Technol, Sch Informat Sci & Engn, Shanghai 200237, Peoples R China;[5]Shanghai Jiao Tong Univ, Sch Med, Shanghai Gen Hosp, Dept Orthoped, Shanghai 200080, Peoples R China

年份：2026

卷号：538

外文期刊名：CHEMICAL ENGINEERING JOURNAL

收录：;EI(收录号：20261920652066);WOS:【SCI-EXPANDED(收录号:WOS:001765859600001)】；

基金：The authors wish to express their gratitude to the financial supports from the National Natural Science Foundation of China (No. 32271401) , the National Key Research and Development Program of China (No. 2022YFC2405702) , and Frontiers Science Center for Materiobiology and Dynamic Chemistry (No. JKVD1211002) . The authors also thank Nan Xu, a rheology engineer at Thermo Fisher Scientific, for providing valuable assistance with the rheological testing.

语种：英文

外文关键词：Solvent-mediated integrated structure; Highly structured solvents; Stiffness-toughness trade-off; Polymer simulation; Robust adhesion; Bio-integrated electronics

摘要：Simultaneous achievement of tissue-like softness, robust durability, and strong adhesion in bio-integrated electronics is impeded by the micro-phase separation and structural heterogeneity inherent in traditional multi-component gels. Herein, we propose a solvent-mediated integrated structure paradigm to resolve this bottleneck. Low-field nuclear magnetic resonance analysis reveals that glycerol exists in a highly structured solvent state within the network, exhibiting highly confined solvent behavior distinct from free-flowing solvents. By leveraging this highly structured nature, this strategy transforms the solvent from a passive dispersion medium into an integral structural component anchored via dense hydrogen bonding. This solvent-polymer integration eliminates discrete phases and creates a homogeneous energy landscape, effectively resolving the intrinsic stiffness-toughness trade-off to achieve rapid photopolymerization, exceptional stretchability (>2000%), and high modulus. Consequently, the PHEAA/Gly system demonstrates robust adhesion (up to 209.6 kPa). Crucially, this strategy is validated as a universal toolkit applicable to diverse acrylate monomers. Beyond mechanical performance, the integrated gel exhibits stable electrical insulation, cytocompatibility and conformal adhesion to biological tissues. Demonstrated through nondestructive device retrieval, ultra-stable interconnects under extreme strain (>900%), and multimodal bio-sensing, this work shifts the design focus from additive complexity to intrinsic solvent-structure engineering, offering a foundational framework for next-generation biointegrated electronics.