文献类型：期刊文献

英文题名：Selective and Efficient Cycloisomerization of Alkynols Catalyzed by a New Ruthenium Complex with a Tetradentate Nitrogen-Phosphorus Mixed Ligand

作者：Liu, Pei Nian[1,2,3];Su, Fu Hai[1];Wen, Ting Bin[1];Sung, Herman H. -Y.[1];Williams, Ian D.[1];Jia, Guochen[1]

机构：[1]Hong Kong Univ Sci & Technol Inst, Dept Chem, Kowloon, Hong Kong, Peoples R China;[2]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2010

卷号：16

期号：26

起止页码：7889

外文期刊名：CHEMISTRY-A EUROPEAN JOURNAL

收录：;EI(收录号：20102813066717);WOS:【SCI-EXPANDED(收录号:WOS:000280431900031)，CCR-EXPANDED(收录号:WOS:000280431900031)】；

基金：This work was supported by the Hong Kong Research Grant Council (project no. HKUST 601709), the Natural Science Foundation of China (NSFC) (project no. 20902020), and the Shanghai Pujiang Talent Program (project no. 09J1403500).

语种：英文

外文关键词：alkynes; isomerization; N,P ligands; ruthenium; vinylidene

摘要：The new ruthenium complex [Ru(N3P)(OAc)][BPh4] (4), in which N3P is the N,P mixed tetradentate ligand N,N-bis[(pyridin-2-yl)methyl]-[2-(diphenylphosphino)phenyl]methanamine was synthesized. The complex was found to be catalytically active for the endo cycloisomerization of alkynols. The catalytic reactions can be used to synthesize five-, six-, and seven-membered endo-cyclic enol ethers in good to excellent yields. A catalytic cycle involving a vinylidene intermediate was proposed for the catalytic reactions. Treatment of complex 4 with PhC CH and H2O gave the alkyl complex [Ru(CH2Ph)(CO)(N3P)]-[BPh4] (30), which supports the assumption that the catalytic reactions involve addition of a hydroxyl group to the C=C bond of vinylidene ligands.