文献类型：期刊文献

英文题名：The evolution of Traditional Chinese Medicine as recombinant inventions

作者：Wu, Min[1];Ma, Tieju[2,3];Zhu, Yan[4];Ren, Hongtao[1];Fu, Lu[5]

机构：[1]East China Univ Sci & Technol, Sch Business, Dept Management Sci & Engn, Shanghai 200237, Peoples R China;[2]Shanghai Jiao Tong Univ, Antai Coll Econ & Management, Dept Informat Technol & Innovat, Shanghai 200030, Peoples R China;[3]Int Inst Appl Syst Anal, A-2361 Laxenburg, Austria;[4]China Acad Chinese Med Sci, Inst Informat Tradit Chinese Med, Beijing 100700, Peoples R China;[5]China Acad Chinese Med Sci, China Inst Hist Med & Med Literature, Beijing 100700, Peoples R China

年份：2024

卷号：121

期号：46

外文期刊名：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001359210100003)】；

基金：We thank the anonymous reviewers for providing valuable comments and suggestions which are very helpful for improving our study. We acknowledge the support of the NSFC for this research. National Natural Science Foundation of China 71125002 (T.J.M.) . National Natural Science Foundation of China 82174534 (Y.Z.).

语种：英文

外文关键词：Traditional Chinese Medicine; network science; recombinant invention; evolution

摘要：It has been widely recognized that technologies evolve with recombinant inventions. However, it remains unknown whether technologies developed using different approaches would exhibit different features during evolution. In particular, would technologies developed mainly based on accumulated experience in practices-formulas of traditional Chinese medicine (TCM) are typical examples of such technologies-have similar evolution features found in modern technologies? This study applied network science to explore the evolution of TCM from the perspective of recombinant inventions based on 59,063 TCM formulas documented over the last two thousand years, with each formula being a combination of components that are mostly herbs. Our results show that similar to modern technological systems, the TCM component networks maintained the core-periphery structures during evolution, and the (weighted) degrees of components followed heavy- tailed distributions. Moreover, simple tuples, which are frequently used combinations of TCM components, serve as building blocks for complex ones. A significant difference with modern technological systems is that the TCM core components were quite stable, while substitutions of core components are frequently observed in modern technological systems, leading to new technological trajectories. TCM comprises ancient knowledge and wisdom. This research provides insight into how it will be like in the future and what is important for its future.