文献类型：期刊文献

英文题名：Controllable release from magnetoliposomes by magnetic stimulation and thermal stimulation

作者：Qiu, Dan[1];An, Xueqin[1]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2013

卷号：104

起止页码：326

外文期刊名：COLLOIDS AND SURFACES B-BIOINTERFACES

收录：;EI(收录号：20131016078403);WOS:【SCI-EXPANDED(收录号:WOS:000316645100047)】；

基金：This work is financially supported by the National Nature Science Foundation of China (21273073 and 21073063), and the National High-Tech Research and Development Plan of China ("863" plan, No.2011AA06A107) and the Fundamental Research Funds for the Central Universities, China (No.WK0913002).

语种：英文

外文关键词：Magnetoliposomes; Microstructure; Release; Switch on and off; Alternating current electromagnetic field

摘要：Liposomes with superparamagnetic iron oxide nanoparticles embedded in membrane were prepared by the supercritical carbon dioxide (scCO(2)) method. The cargos can be released from liposomes by both triggered agents, temperature and alternating current electromagnetic field (AMF). The release mechanism was explained from the view of microstructure change investigated by fluorescence probe method. The contents could be repetitively released from liposomes controlled by switching on and off the AMF. The results indicated that the release from the liposomes was due to the magnetocaloric effect resulting in the liposome phase transition and the magnetic-impelled motions leading to the improved bilayer permeability, rather than the destruction of the liposome structure. (c) 2012 Elsevier B.V. All rights reserved.