文献类型：期刊文献

英文题名：A dynamic charge-dependent nanofungicide platform for sustainable agrochemical deposition and delivery

作者：Yu, Miaojie[1,2,3,4];Wang, Jia[1];Wu, Yue[1];Yuan, Chen[1];Cao, Ran[1];Rotello, Vincent M.[5];Huang, Qingchun[6];Xu, Yisheng[1,2];Zhu, Wei-Hong[2,3,4]

机构：[1]East China Univ Sci & Technol, Sch Chem Engn, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Ctr Photosensit Chem Engn, State Key Lab Green Chem Engn & Ind Catalysis, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem,Sch Che, Inst Fine Chem,Key Lab Adv Mat,Shanghai Key Lab Fu, Shanghai 200237, Peoples R China;[4]East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Mat Biol & Dynam Chem,Sch Chem &, Inst Fine Chem,Joint Int Res Lab Precis Chem & Mol, Shanghai 200237, Peoples R China;[5]Univ Massachusetts Amherst, Dept Chem, 710 North Pleasant St, Amherst, MA 01003 USA;[6]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2026

卷号：12

期号：7

外文期刊名：CHEM

收录：;WOS:【SCI-EXPANDED(收录号:WOS:001822801500001)】；

基金：We gratefully acknowledge funding from the Basic Science Center of National Natural Science Foundation of China (T2488302) , National Natural Science Foundation of China (NSFC 22378126, 92356301, and 22338006) , Science and Technology Commission of Shanghai Municipality (25ZR1402115) . We acknowledge Jiangsu Qizhou Green Chemical Co. Ltd for assistance with the field experiment. We acknowledge Anqi Li and Xiaofei Xu forthe assistance with MD simulations.

语种：英文

摘要：Utilization efficiency of sprayed agrochemicals is typically limited by weak adhesion to plant cuticles with ineffective retention. Increasing surface positive charge is effective to strengthen the adhesion, while often overlooking the restricted uptake caused by excessively strong surface binding. Here, we report a unique "dynamic" surface-charge-featured nanofungicide platform for overcoming the dilemma, enabling synergistic enhancement of deposition and uptake. Besides precisely enhancing positivity of nanocarriers via oppositely charged polymers for strong adhesion, we incorporate a thermo-responsive unit to enable in situ mitigation of surface charge in response to temperature after deposition, avoiding excessive positive charge with impaired subsequent uptake. The tebuconazole nanofungicide achieves a curative effect of 98% against B. cinerea on tomato plants using only half the standard dosage. Given the scale-up production from flash nanoprecipitation engineering, the dynamic charge of the nanofungicide makes for a promising feasibility for real-world sustainable agriculture and offers innovative strategies to enhance utilization efficiency with minimized agrochemical inputs.