详细信息
Fc-PIP Catalyzed Asymmetric Synthesis of cis-2,3-Dihydrobenzofurans
文献类型:期刊文献
中文题名:Fc-PIP Catalyzed Asymmetric Synthesis of cis-2,3-Dihydrobenzofurans
作者:Shanshan Jiang[1];Bin Hu[1];Xingxin Yu[1];Weiping Deng[1]
机构:[1]Shanghai Key Laboratory of New Drug Design,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China
年份:2014
卷号:32
期号:8
起止页码:694
中文期刊名:Chinese Journal of Chemistry
外文期刊名:中国化学(英文版)
收录:CSTPCD;;Scopus;CSCD:【CSCD2013_2014】;PubMed;
基金:The authors are grateful to the Fundamental Research Funds for the Central Universities,the National Natural Science Foundation of China(No.21372074).
语种:英文
中文关键词:Michael addition-Lactonization;dihydrobenzofuran;Fc-PIP
摘要:A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst(Fc-PIP)was developed,furnishing cis-2,3-dihydrobenzofuran derivatives with excellent enantioselecitivities(94%-98%ee)and good diastereoselectivities(up to 99/1).
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