文献类型：期刊文献

英文题名：Three-component hetero-domino cyclization and copper-catalyzed double A3-coupling reaction of ethane-1,2-diamines, formaldehyde, and alkynes to afford 1,3-dipropargylimidazolidines

作者：Sun, Lu[1];Wu, Mengying[1];Huang, Xi[1];Wang, Jiayi[1];Song, Gonghua[1]

机构：[1]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, 130 Meilong Rd, Shanghai 200237, Peoples R China

年份：2018

卷号：54

期号：3

起止页码：355

外文期刊名：CHEMISTRY OF HETEROCYCLIC COMPOUNDS

收录：;EI(收录号：20242616487910);WOS:【SCI-EXPANDED(收录号:WOS:000434260200017)，CCR-EXPANDED(收录号:WOS:000434260200017)】；

基金：Financial support for this work from the National Key R&D Program (Grant No. 2017YFD0200504), the National Natural Science Foundation of China (grant No. 21572060), and the Shanghai Key Laboratory of Catalysis Technology for Polyolefins (LCTP-201301) is gratefully acknowledged.

语种：英文

外文关键词：1,3-dipropargylimidazolidines; A(3)-coupling; copper catalysis; cyclization; hetero-domino reaction; three-component reaction

摘要：A novel and efficient approach to the synthesis of 1,3-dipropargylimidazolidines via a hetero-domino cyclization and copper-catalyzed double A(3)-coupling reaction of ethane-1,2-diamines, formaldehyde, and alkynes has been reported. The transformation provides a useful method for the synthesis of imidazolidine derivatives.