文献类型：期刊文献

英文题名：Synthesis of branched PEG brushes hybrid hydrophilic magnetic nanoparticles for the selective enrichment of N-linked glycopeptides

作者：Xiong, Zhichao[1,2];Zhao, Liang[1];Wang, Fangjun[1];Zhu, Jun[1];Qin, Hongqiang[1];Wu, Ren'an[1];Zhang, Weibing[1,2];Zou, Hanfa[1]

机构：[1]Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Natl Chromatog R&A Ctr, Dalian 116023, Peoples R China;[2]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 20023, Peoples R China

年份：2012

卷号：48

期号：65

起止页码：8138

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000306573800031)】；

基金：Financial support is gratefully acknowledged from the National Natural Sciences Foundation of China (20975101), the Creative Research Group Project by NSFC (21021004), the China State Key Basic Research Program Grant (2012CB910101) and the Analytical Method Innovation Program of MOST (2009IM031800, 2010IM030500) to H. F. Zou.

语种：英文

摘要：Hybrid Fe3O4@SiO2@PEG-Maltose MNPs were synthesized by SI-ATRP of branched PEG brushes on the surface and subsequent functionalization with hydrophilic maltose group, and the multifunctional materials were utilized for selective enrichment of N-linked glycopeptides from biological samples with high specifity, high sensitivity, and large binding capacity.