文献类型：期刊文献

英文题名：East China University of Science and Technology

作者：Wang, Fei[1]; Teng, Jiangge[1]; Li, Zixu[1]; Fang, Chao[1]; Ma, Kai[1]; Ke, Yanxiong[1]; Jia, Qiang[2]; Chu, Changhu[1]

机构：[1] Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China; [2] Seasons Biotechnology [Taizhou] Co., Ltd., 21 Jiutiao Road, Jiaojiang District, Zhejiang, Taizhou, 318000, China

年份：2024

外文期刊名：SSRN

收录：EI(收录号：20240132712)

语种：英文

外文关键词：Catalyst activity - Chemical reactions - Metal halides

摘要：A facile and readily available Fe-ppm-Pd/C catalyst has been developed for catalyzing Suzuki-Miyaura cross-coupling reactions. When combined with Sphos (dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphane), this catalyst with low levels of palladium (as low as 180ppm), efficiently facilitates cross-coupling reactions between aryl boronic acids (aryl neopentyl-1,3-diol boronic ester) and a wide range of aryl halides. Additionally, the recovered Fe-ppm-Pd/C catalyst has demonstrated sustained catalytic activity over four runs, indicating minimal decline in performance. This suggests the catalyst's potential for long-term use and its practicality in industrial applications. ? 2024, The Authors. All rights reserved.