文献类型：期刊文献

英文题名：Evaluation of a novel self-emulsifiable dodecenyl succinylated agarose in microencapsulation of docosahexaenoic acid (DHA) through spray-chilling process

作者：Xiao, Qiong[1,2,3];Chen, Guo[2];Zhang, Yonghui[1,3,4];Weng, Huifen[1,3,4];Cai, Menghao[5];Xiao, Anfeng[1,3,4]

机构：[1]Jimei Univ, Coll Food & Biol Engn, Xiamen 361021, Peoples R China;[2]Huaqiao Univ, Dept Biotechnol & Bioengn, Xiamen 361021, Peoples R China;[3]Natl R&D Ctr Red Alga Proc Technol, Xiamen 361021, Peoples R China;[4]Fujian Prov Engn Technol Res Ctr Marine Funct Foo, Xiamen 361021, Peoples R China;[5]East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

年份：2020

卷号：163

起止页码：2314

外文期刊名：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

收录：;EI(收录号：20235015202861);WOS:【SCI-EXPANDED(收录号:WOS:000579839600225)】；

基金：This work was supported by National Natural Science Foundation of China (21576108), Projects of Science and Technology Program of Xiamen City (3502Z20183030), University-enterprise Cooperation of Fujian Province (2016N5008) and National Marine Economic Innovation and Development Demonstration Project (PD-HY-008).

语种：英文

外文关键词：Agarose sodium dodecenyl succinate; Spray-chilling process; Docosahexaenoic acid microencapsulation

摘要：Agarose is a potential wall material for encapsulation owing to its high oxygen barrier, but its high hydrophilia and low emulsifying activity restrict its application as a wall material for hydrophobic actives. The aim of this study was to evaluate the potential of a novel self-emulsifiable dodecenyl succinic anhydride-esterified agarose (DSAG) as a single emulsifier and a wall material to encapsulate DHA. Results showed that DSAG was suitable for DHA encapsulation via spray-chilling process, and DHA microcapsules with different sizes (100-400 mu m) could be easily prepared by controlling the spray pressure. The encapsulation efficiency of DSAG reached as high as 65-85%. The wet microcapsules were nearly spherical but they showed cavities or wrinkles on the surface after freeze drying. The DHA microcapsules, whether dry or wet or of different sizes, showed excellent oxidative stability, and exhibited good release characteristics under the simulated gastric and intestinal fluid conditions. (C) 2020 Elsevier B.V. All rights reserved.