文献类型：期刊文献

中文题名：含钠碱选择性催化乙腈环三聚反应

英文题名：Selective Cyclotrimerization of Acetonitrile Catalyzed by Sodium-Based Alkali

作者：陶晓春[1];陶辉[1];刘涛平[1];钱延龙[1];

机构：[1]The Laboratory of Organometallic Chemistry, East China University of Science and Technology,Shanghai 200237, China;

年份：2002

卷号：23

期号：2

起止页码：99

中文期刊名：催化学报

外文期刊名：CHINESE JOURNAL OF CATALYSIS

收录：CSTPCD;;Scopus;北大核心:【北大核心2000】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：acetonitrile,cyclotrimerization,4-amino-2,6-dimethylpyrimidine,sodium-based alkali

外文关键词：acetonitrile,cyclotrimerization,4-amino-2,6-dimethylpyrimidine,sodium-based alkali

摘要：4-amino-pyrimidine not only has important biological activity[1], but also is the intermediate for some medicines. It can be prepared by cyclotrimerization of nitriles. Meyer[2] found that acetonitrile could be cyclotrimerized to 4-amino-2,6-dimethyl-pyrimidine in the presence of sodium. Excess sodium methoxide or potassium methoxide reacts with acetonitrile to give this product in a sealed equipment at 140 ℃ for 5 h with 70%～80% yield[3,4].