文献类型：期刊文献

英文题名：Theophylline Molecular Imprinted Composite Membranes Prepared on a Ceramic Hollow Fiber Substrate

作者：Ye, Yi-Ting[1];Ma, Xiao-Hua[1];Xu, Zhen-Liang[1];Zhang, Ying[1]

机构：[1]E China Univ Sci & Technol, Chem Engn Res Ctr, State Key Lab Chem Engn, Membrane Sci & Engn R&D Lab, Shanghai 200237, Peoples R China

年份：2014

卷号：53

期号：1

起止页码：346

外文期刊名：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

收录：;EI(收录号：20140317214659);WOS:【SCI-EXPANDED(收录号:WOS:000329586100039)】；

基金：The authors are thankful for the financial support from the National Natural Science Foundation of China (20076009, 21176067, and 21276075).

语种：英文

外文关键词：Surface roughness - Synthesis (chemical) - Alumina - Atomic force microscopy - Ethylene glycol - Ethylene - Free radicals - Fourier transform infrared spectroscopy - Molecules - Pore size - Aluminum oxide - Atom transfer radical polymerization - Ceramic membranes - Scanning electron microscopy

摘要：Theophylline (THO) molecular imprinted composite membranes (MIM) were successfully prepared by thermal-initiated free radical polymerization on the surface of alpha-Al2O3 ceramic microporous hollow fiber substrate membranes. Molecular imprinted polymerization layer was synthesized by taking theophylline as the template molecule, methacrylic acid (MAA) as the functional monomer, ethylene glycol dimethacrylate (EDMA) as the cross-linker, and 2,2'-azobisisobutyronitrile (AIBN) as the free-radical initiator. After polymerization and the elution of the imprinted molecule, the R-max (the maximum pore size) upon the membrane surface decreased from 2.8 to 1.9 mu m. The imprinted layer upon the ceramic membranes was investigated by scanning electron microscopy (SEM), atomic force microscope (AFM) and Fourier transform infrared spectroscopy (FTIR). SEM micrographs showed a 1 mu m thick composite membrane, and AFM showed different surface roughness. Moreover, the selectivity separation factor of theophylline (THO) to theobromine (TB) was determined as 2.63 in a mixed feed solution, thus suggesting that the imprinting process allowed for preferential permeance and affinity selectivity to THO.