文献类型：期刊文献

英文题名：Aggregation behavior of N-carboxyethylchitosan in aqueous solution: effects of pH, polymer concentration, and presence of a gemini surfactant

作者：Peng, Baoliang[1]; Hao, Yongliang[1]; Kang, Hongmei[1]; Han, Xia[1]; Peng, Changjun[1]; Liu, Honglai[1]

机构：[1] Key Laboratory for Advanced Materials, Department of Chemistry, East China University of Science and Technology, Shanghai, 200237, China

年份：2010

卷号：345

期号：1

起止页码：101

外文期刊名：Carbohydrate Research

收录：EI(收录号：20095112555892)

语种：英文

外文关键词：Agglomeration - Addition reactions - Biocompatibility - pH effects - Phase separation - Solutions - Surface active agents

摘要：A kind of biocompatible derivative of chitosan, N-carboxyethylchitosan (CECh) with a degree of substitution of 0.21 (DS 0.21) was synthesized by a Michael addition reaction. The aggregation behavior of CECh in aqueous solution under the effects of pH, polymer concentration, as well as a gemini surfactant, was investigated by turbidity, zeta potential, fluorescence spectroscopy, viscosity, and surface tension measurements. In the pH range of 3-11, the macroscopic phase separation of CECh from water occurs near the isoelectric point (IEP) due to the intense electrostatic attraction, and the intermolecular interaction at pH 4 is stronger than that at pH 10 over the whole CECh concentration region. The critical aggregation concentration (CAC) of CECh/12-n-12 (n = 3, 6) in basic media is determined to be between 0.0010 and 0.0015 mmol/L, and the length of the surfactant spacer is found to play an important role in the interaction of 12-n-12 with CECh. ? 2009 Elsevier Ltd. All rights reserved.