文献类型：期刊文献

英文题名：Lanthanum Pentafluorobenzoate-Catalyzed Aerobic Oxidative Olefination of Benzylamines with 2-Methylquinoline through Deamination and C-H Bond Functionalization

作者：Mao, Dan[1,2];Zhu, Xiaoyan[1,2];Hong, Gang[1,2];Wu, Shengying[1,2];Wang, Limin[1,2,3]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Key Lab Organofluorine Chem, Shanghai Inst Organ Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

年份：2016

卷号：27

期号：17

起止页码：2481

外文期刊名：SYNLETT

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000386125700014)，CCR-EXPANDED(收录号:WOS:000386125700014)】；

基金：This research was financially supported by the National Nature Science Foundation of China (21272069, 20672035) and the Fundamental Research Funds for the Central Universities and Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.

语种：英文

外文关键词：quinolines; C-H functionalization; olefination; oxidation; Lewis acid

摘要：An efficient direct aerobic oxidative olefination of the methyl groups of 2-methylquinolines with benzylamines in the presence of a rare-earth-metal Lewis acid catalyst to give 2-styrylquinolines was successfully developed. Preliminary mechanistic studies revealed that the oxidative olefination reaction proceeds through a Lewis acid-catalyzed 2-methylquinoline-aldehyde condensation and an amine-aldehyde condensation.