文献类型：期刊文献

英文题名：Colorimetric logic gates based on aptamer-crosslinked hydrogels

作者：Yin, Bin-Cheng[1];Ye, Bang-Ce[1];Wang, Hui[2,3];Zhu, Zhi[2,3];Tan, Weihong[2,3]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Lab Biosyst & Microanal, Shanghai 200237, Peoples R China;[2]Univ Florida, Dept Chem, Ctr Res Bio Nano Interface, Gainesville, FL 32611 USA;[3]Univ Florida, Physiol & Shands Canc Ctr, Gainesville, FL 32611 USA

年份：2012

卷号：48

期号：9

起止页码：1248

外文期刊名：CHEMICAL COMMUNICATIONS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000298943600013)】；

基金：This work was financially supported by NSF21075040, the Shanghai 11XD1401900, 09JC1404100, and the Fundamental Research Funds for the Central Universities. We thank the National Institutes of Health (GM066137, GM079359 and CA133086) for supporting this research. We also thank Da Han, Jian Wang, Jin Huang, Mingxu You, Yan Chen, Xiaohong Tan and Lu Peng for valuable discussions and assistance on the experiment design.

语种：英文

摘要：We have developed a novel molecular logic gate system based on the incorporation of aptamer-crosslinked hydrogels. Modified gold nanoparticles are used as the output signal, which is visible to the naked eye. This system is designed for AND and OR operations using two chemicals as stimulus inputs.