文献类型：期刊文献

英文题名：β-blockers in the environment: Distribution, transformation, and ecotoxicity

作者：Yi, Ming[1];Sheng, Qi[1];Sui, Qian[2];Lu, Huijie[1]

机构：[1]Zhejiang Univ, Coll Environm Resource Sci, Key Lab Environm Remediat & Ecol Hlth, Minist Educ, Hangzhou 310058, Peoples R China;[2]East China Univ Sci & Technol, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China

年份：2020

卷号：266

外文期刊名：ENVIRONMENTAL POLLUTION

收录：;EI(收录号：20203409093593);WOS:【SCI-EXPANDED(收录号:WOS:000571665100004)】；

基金：This work was supported by Major Science and Technology Program for Water Pollution Control and Treatment (2017ZX07206002) and the Fundamental Research Funds for the Central Universities (2019FZJD007).

语种：英文

外文关键词：beta-blocker; Distribution; Transformation; Ecotoxicity

摘要：beta-blockers are a class of medications widely used to treat cardiovascular disorders, including abnormal heart rhythms, high blood pressure, and angina pectoris. The prevalence of beta-blockers has generated a widespread concern on their potential chronic toxicity on aquatic organisms, highlighting the necessity of comprehensive studies on their environmental distribution, fate, and toxicity. This review summarizes the up-to-date knowledge on the source, global distribution, analytical methods, transformation, and toxicity of beta-blockers. Twelve beta-blockers have been detected in various environmental matrices, displaying significant temporal and spatial variations. beta-blockers can be reduced by 0-99% at wastewater treatment plants, where secondary processes contribute to the majority of removal. Advanced oxidation processes, e.g., photocatalysis and combined UV/persulfate can transform beta-blockers more rapidly and completely than conventional wastewater treatment processes, but the transformation products could be more toxic than the parent compounds. Propranolol, especially its (S)-enantiomer, exhibits the highest toxicity among all beta-blockers. Future research towards improved detection methods, more efficient and cost-effective removal techniques, and more accurate toxicity assessment is needed to prioritize beta-blockers for environmental monitoring and control worldwide. (C) 2020 Elsevier Ltd. All rights reserved.