文献类型：期刊文献

英文题名：IN SITU POLYMERIZATION OF PYRROLE IN MESOPOROUS SILICA AND APPLICATION TO ELECTRODE MODIFICATION

作者：Han, Xiao[1];Zhu, Yihua[1];Yang, Xiaoling[1];Luan, Shaorong[2]

机构：[1]E China Univ Sci & Technol, Minist Educ, Sch Mat Sci & Engn, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Res Ctr Anal & Test, Shanghai 200237, Peoples R China

年份：2010

卷号：15

期号：3

起止页码：155

外文期刊名：INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000277459800003)】；

基金：This work was supported by the National Natural Science Foundation of China (20676038, 20976054), the Key Project of Science and Technology for Ministry of Education (107045), the Innovation Program of Shanghai Municipal Education Commission (09ZZ58), the Program of Shanghai Subject Chief Scientist (08XD1401500), the Shuguang Scholar-Tracking Foundation of Shanghai (08GG09), and the Shanghai Leading Academic Discipline Project (project number: B502).

语种：英文

外文关键词：Biosensors; Conducting polymers; Electrochemistry; Nanocomposites; Polypyrroles

摘要：A hybrid system of mesoporous silica (MS) particles coated with polypyrrole (PPy) was constructed through chemical polymerization of pyrrole in the presence of the MS particles. The MS-PPy composite particles with immobilized hemoglobin (Hb) were used to modify a glassy carbon electrode (GCE) for detecting the electrocatalytic response to the reduction of hydrogen peroxide. The structure of composite particles and the performance of biosensors were characterized by SEM, TEM, FT-IR, cyclic voltammetry (CV), and amperometric measurements, respectively. The results show that the PPy shell is uniformly coated over the silica surface without using any agent to modify the MS particles. Under optimal conditions, the sensors had a fast response of hydrogen peroxide (H2O2). The catalytic currents are linearly proportional to the concentrations of H2O2 in the range from 0.01 to 1.2 mM, and the corresponding detection limits are 0.01 mM (S/N = 3).