文献类型：专利

英文题名：Expression construct for regulating binary signal of exogenous protein, and inoculating attenuated vaccine strain to produce vaccine for immunizing animals against Edwardsiella, comprises bacterial population sensing system coding sequence

作者：LIU Q;WANG P;WANG Q;ZHANG Y;XIAO J;CHU T

机构：[1]UNIV EAST CHINA SCI & TECHNOLOGY;[2]SHANGHAI WEISHENG MARINE BIOTECHNOLOGY

申请号：CN105779486-A

申请日：2014-12-19

公开日：2016-07-20

语种：英文

收录：DERWENT

摘要：NOVELTY - Expression construct comprises bacterial population sensing system coding sequence, arabinose promoter araC-ParaBAD for regulating expression of bacterial population quenching gene aiiA sequence, and are operatively connected. USE - Expression construct for regulating binary signal of exogenous protein, and inoculating attenuated vaccine strain containing WED vector to produce vaccine for immunizing animals against Edwardsiella tarda (all claimed). DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for regulating expression of exogenous protein, which involves transforming host bacterium using expression construct, when host strain is in arabinose-containing environment then exogenous protein expression is not observed, and then when host strain is in arabinose-lacking environment then exogenous protein expression is observed.