文献类型：期刊文献

英文题名：A senolytic strategy integrating multiple technologies delays aging

作者：Guo, Yuan[1];Li, Jian[2]

机构：[1]Northwest Univ, Xian, Peoples R China;[2]East China Univ Sci & Technol, Shanghai, Peoples R China

年份：2023

外文期刊名：NATURE AGING

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000962879800001)】；

语种：英文

摘要：Cellular senesence is believed to be a driver of aging. We designed and synthesized a photosensitive prodrug that destroys senescent cells by integrating multiple technologies that combine biomarker guidance with a fluorescence tag, target-site anchoring and photodynamic therapy, providing a strategy for monitoring and specifically eliminating senescent cells to regulate aging.