文献类型：期刊文献

英文题名：Highly Sensitive and Selective Nonenzymatic Detection of Glucose Using Three-Dimensional Porous Nickel Nanostructures

作者：Niu, Xiangheng[1,2];Lan, Minbo[1,2,3];Zhao, Hongli[1,2,4];Chen, Chen[1,2]

机构：[1]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Res Ctr Anal & Test, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Minist Educ, Key Lab Ultrafine Mat, Shanghai 200237, Peoples R China;[4]E China Univ Sci & Technol, Inst Appl Chem, Shanghai 200237, Peoples R China

年份：2013

卷号：85

期号：7

起止页码：3561

外文期刊名：ANALYTICAL CHEMISTRY

收录：;EI(收录号：20131516191105);WOS:【SCI-EXPANDED(收录号:WOS:000317173200018)】；

基金：This research was financially supported by Science and Technology Commission of Shanghai Municipality (No. 10391901600) and Ministry of Education of the People's Republic of China (No. WK1014051).

语种：英文

外文关键词：Electrochemical electrodes - Nickel - Signal to noise ratio - High resolution transmission electron microscopy - Scanning electron microscopy - X ray diffraction analysis - Catalytic oxidation - Electrooxidation - Electrochemical sensors - Nanostructures

摘要：Highly sensitive and selective nonenzymatic detection of glucose has been achieved using a novel disposable electrochemical sensor based on three-dimensional (3D) porous nickel nanostructures. The enzyme-free sensor was fabricated through in situ growing porous nickel networks on a homemade screen-printed carbon electrode substrate via electrochemically reducing the Ni2+ precursor, along with continuously liberating hydrogen bubbles. The resulting nickel-modified electrode was characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy-dispersive X-ray spectrometry (EDX), powder X-ray diffractometry (XRD), and electrochemical techniques. Cyclic voltammetric, alternating-current impedance, and amperometric methods were used to investigate the catalytic properties of the assembled sensor for glucose electro-oxidation in alkaline media. Under optimized conditions, the enzymeless sensor exhibited excellent performance for glucose analysis selectively, offering a much wider linear range (from 0.5 mu M to 4 mM), an extremely low detection limit (0.07 mu M, signal-to-noise ratio (S/N) of 3), and an ultrahigh sensitivity of 2.9 mA/(cm(2) mM). Importantly, favorable reproducibility and long-term performance stability were obtained thanks to the robust frameworks. Application of the proposed sensor in monitoring blood glucose was also demonstrated.