文献类型：期刊文献

中文题名：有机氮源对红霉素发酵影响的具体分析

英文题名：Effect on organic nitrogen source on the erythromycin fermentation

作者：卞晨光[1];宫衡[1];付水林[1]

机构：[1]华东理工大学生物反应器工程国家重点实验室,上海200237

年份：2005

卷号：30

期号：4

起止页码：193

中文期刊名：中国抗生素杂志

外文期刊名：Chinese Journal of Antibiotics

收录：CSTPCD;;Scopus;北大核心:【北大核心2004】；CSCD:【CSCD2011_2012】；

语种：中文

中文关键词：红霉素;有机氮源;逐步回归分析;苏氨酸

外文关键词：Erythromycin; Organic nitrogen source; Stepwise regression analysis; Threonine

摘要：红色糖多孢菌的摇瓶培养基中使用不同有机氮源时红霉素的效价明显不同。通过对不同有机氮源所含营养成分的逐步回归分析,我们得到有机氮源中的苏氨酸为影响红霉素效价的主要因子。最后向对照培养基中添加苏氨酸,则使红霉素的效价比对照培养基提高了22.85%。
The production of erythromycin in the shake flask was significantly influenced by adding different kinds of organic nitrogen source (e.g. amino acids). With stepwise regression method, the effect of components in the different organic nitrogen source were analyzed. Result showed that the threonine was the most important affecting the erythromycin productivity. When it was added to the fermentation medium, the production of erythromycin increased by 22.85% than the control.