文献类型：期刊文献

中文题名：红外光谱技术在生物过程监测中的应用

英文题名：Application of Infrared Spectroscopy to Monitoring the Bioprocesses

作者：邱江[1];叶勤[1];张嗣良[1]

机构：[1]华东理工大学生物反应器国家重点实验室

年份：1998

卷号：14

期号：1

起止页码：1

中文期刊名：生物工程学报

外文期刊名：Chinese Journal of Biotechnology

收录：CSTPCD;;Scopus;北大核心:【北大核心1996】；CSCD:【CSCD2011_2012】；PubMed;

语种：中文

中文关键词：红外光谱;发酵过程;细胞培养

外文关键词：Fourier transform infrared (FTIR),attenuated total reflection (ATR),process analysis,bioprocesses,fermentation

摘要：在线监测化学组分的浓度对许多生物过程都是十分必要的。然而，探头需耐高温灭菌的要求和生物体系自身的复杂性给许多分析技术的在线监测带来了困难。近几年，随仪器和数据处理技术的迅速发展，应用红外光谱技术对生物过程的原位或在线监测日益广泛。本文对红外过程分析技术进行了较全面的综述，介绍了红外分析的原理、进展及在生物过程监测中的应用。
On line measuring concentrations of chemical components is of fundamental importance in many bioprocesses.However,the on line measurement is very difficult to make for many analytical techniques because of the requiring sterilization of probes and the complexity of the bioprocesses.Rapid advances in instrumentation and data processing techniques in recent years have allowed infrared spectroscopy to be increasingly applied to in situ or on line monitoring bioprocesses.The basic principle and recent developments of infrared process analysis are introduced .In addition,the application of infrared spectroscopy in monitoring bioprocesses are reviewed.