文献类型：期刊文献

英文题名：Identification of indicator PPCPs in landfill leachates and livestock wastewaters using multi-residue analysis of 70 PPCPs: Analytical method development and application in Yangtze River Delta, China

作者：Wu, Dongquan[1];Sui, Qian[1,4];Yu, Xia[1];Zhao, Wentao[2];Li, Qiang[3];Fatta-Kassinos, Despo[5,6];Lyu, Shuguang[1,4]

机构：[1]East China Univ Sci & Technol, Sch Resources & Environm Engn, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[2]Tongji Univ, Coll Environm Sci & Engn, State Key Lab Pollut Control & Resource Reuse, Shanghai 200092, Peoples R China;[3]Shimadzu China Co Ltd, Shanghai 200233, Peoples R China;[4]Shanghai Inst Pollut Control & Ecol Secur, Shanghai 200092, Peoples R China;[5]Univ Cyprus, Int Water Res Ctr, Dept Civil & Environm Engn, POB 20537, CY-1678 Nicosia, Cyprus;[6]Univ Cyprus, Int Water Res Ctr, Nireas, POB 20537, CY-1678 Nicosia, Cyprus

年份：2021

卷号：753

外文期刊名：SCIENCE OF THE TOTAL ENVIRONMENT

收录：;EI(收录号：20203609139458);WOS:【SCI-EXPANDED(收录号:WOS:000588616700006)】；

基金：This research was partly supported by the National Natural Science Foundation of China (21777042, 21577033, and 51408425), the Major Science and Technology Programfor Water Pollution Control and Treatment in China (2017ZX07202006), the Fundamental Research Funds for the Central Universities and Beijing Key Laboratory for Emerging Organic Contaminants Control.

语种：英文

外文关键词：Pharmaceuticals and personal care products (PPCPs); Landfill leachate; Livestock wastewater; Indicator PPCPs (i-PPCPs); Non-antibiotics

摘要：The source apportionment of pharmaceuticals and personal care products (PPCPs) in the water environment based on indicators (i-PPCPs) requires a comprehensive characterization of various emission sources using reliable analytical methods for a wide spectrum of PPCPs. In this study, a robust and sensitive method based on solid phase extraction (SPE) and ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) for analyzing 70 PPCPs belonging to 17 therapeutic classes in landfill leachates and livestock wastewaters was developed. The SPE cartridges, sample pH, elution solvents and chelating agent additions were optimized, and acceptable recoveries (60-130% for 67 target compounds), low method quantification limits (landfill leachate: 3-1309 ng/L; livestock wastewater: 3-686 ng/L) and high precisions (repeatability: 0-20% for over 99% injections; reproducibility: 0-20% for over 90% injections) were obtained. Using the optimized analytical method to characterize PPCPs in the typical landfill leachate and livestock wastewater in Yangtze River Delta, China, we found anthelmintics, which were first reported in landfill leachates globally, exhibited the highest concentration (albendazole, maximum concentration of 61.6 mu g/L), and therefore proposed albendazole as one of the promising i-PPCP candidates in landfill leachates. In livestock wastewaters, antibiotics lincomycin was the most abundant PPCP (maximum concentration: 735 mu g/L) and identified as an i-PPCP candidate for livestock-originated contamination. In addition, 15 non-antibiotic PPCPs were first investigated in the livestock wastewater in China and some non-steroidal anti-inflammatory drugs, acetaminophen, diclofenac and naproxen, were detected at similar concentration level (1.16-91.1 mu g/L) to antibiotics, highlighting the necessity to include representative non-antibiotic PPCPs in the studies of emerging contaminants in livestock wastewaters. The developed method provides a tool to comprehensively investigate PPCPs in high-strength wastewater, and the preliminary findings in the characterization of typical landfill leachates and livestock wastewaters are helpful to select i-PPCPs for the source apportionment of PPCPs in Yangtze River Delta, China. (C) 2020 Elsevier B.V. All rights reserved.