文献类型：期刊文献

中文题名：应用单纯自固化磷酸钙人工骨修复小儿良性骨肿瘤术后骨缺损

英文题名：REPAIR OF BONE DEFECT DUE TO TUMOUR RESECTION WITH SELF-SETTING CALCIUM PHOSPHATE CEMENT IN CHILDREN

作者：陈秋[1];周永德[2];马瑞雪[2];吉士俊[2];陈莺[2];刘昌胜[3]

机构：[1]复旦大学附属儿科医院小儿外科,上海200032;[2]中国医科大学第二临床学院小儿骨科;[3]教育部医用生物材料工程研究中心华东理工大学生物材料研究所

年份：2003

卷号：17

期号：6

起止页码：450

中文期刊名：中国修复重建外科杂志

外文期刊名：Chinese Journal of Reparative and Reconstructive Surgery

收录：MEDLINE(收录号：14663939);CSTPCD;;Scopus;CSCD:【CSCD2011_2012】；PubMed;

语种：中文

中文关键词：自固化磷酸钙人工骨;修复;小儿;良性骨肿瘤;术后;骨缺损

外文关键词：Self-setting calcium phosphate cement artificial bone Benign bone tumour Bone defect Children Repair

摘要：目的　探讨应用单纯自固化磷酸钙人工骨 (CPC)修复小儿良性骨囊肿术后骨缺损的临床效果。　方法　 1998年 12月～ 2 0 0 2年 5月随机选取 2 2例良性骨肿瘤患儿 ,男 18例 ,女 4例 ,年龄 4～ 10岁 ,平均 8.3岁。其中非骨化性纤维瘤 11例 ,骨样骨瘤 7例 ,骨囊肿 2例 ,纤维异样增殖症 2例。骨缺损部位 :股骨 14例 ,胫骨 6例 ,肱骨 2例。骨缺损范围 :2 cm× 2 cm× 3cm～ 3cm× 3cm× 6 cm。其中 2 0例采用病灶清除后 CPC松质骨粒填充 ,2例骨囊肿采用穿刺抽液后注射可注射型 CPC。随访时间 :5～ 4 8个月 ,平均 2 3.5个月。　结果　 2 2例均获随访 ,术后均无过敏及毒性反应 ,切口局部无异常 ,骨质生长良好 ,无 1例复发 ,患儿肢体活动正常。　结论　应用单纯 CPC修复小儿良性骨肿瘤术后骨缺损是一种安全、经济、无损伤和简便的方法。
Objective To study the effect of self-setting calcium phosphate cement (CPC) on the repair of local bone defects after resection of cyst in children. Methods From December 1998 to May 2002, 22 patients with bone defects were repaired with CPC. Their ages ranged from 4 to 10 years with an average of 8.3 years. There were 11 cases of non-ossifying fibroma, 7 cases of osteoid osteoma, 2 cases of bone cyst and 2 cases of fibrous dysplasia. The bone defects are located as the following: femur in 14 cases, tibia in 6 cases and humerus in 2 cases. CPC spongiosa granules were filled in 11 cases, injectable CPC were filled in 2 bone cyst cases. The patients were followed up for 5-48 months, averaged 23.5 months. Results Bone matrix grew well and no recurrence was found. Conclusion The method with simple CPC in repairing bone defects is safe, non-toxic, economic and convenient in children.