文献类型：期刊文献

英文题名：Synthesis of Fluoroalkylated Allylic-β-hydroxyesters and Fluoroalkylated β,Y-Epoxy Esters from Ethyl 3-Hydroxy-4-pentenoate

作者：Fang Xiang[1,2];Xiong Ying[1,2];Wang Qiong[1,2];Zhao Min[1,2];Wu Fanhong[1,2,3]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Adv Mat Lab, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Shanghai Inst Technol, Sch Chem & Environm Engn, Shanghai 200235, Peoples R China

年份：2011

卷号：29

期号：12

起止页码：2669

外文期刊名：CHINESE JOURNAL OF CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000298016700017)】；

基金：Project supported by the National Natural Science Foundation of China (NNSFC) (Nos. 20972050, 21172148).

语种：英文

外文关键词：ethyl 3-hydroxy-4-pentenoate; fluoroalkylated allylic-beta-hydroxyesters; fluoroalkylated beta,gamma-epoxy esters

摘要：A sequential transformation of fluoroalkylated adducts obtained from ethyl 3-hydroxy-4-pentenoate with fluorinated iodides was reported. The dehydrohalogenation of adducts was favored to give fluoroalkylated unsaturated beta-hydroxy esters in the presence of triethylamine. And intramolecular S(N)2 reaction products, fluoroalkylated beta,gamma-epoxy esters, were obtained in 10% aqueous sodium carbonate solution.