文献类型：期刊文献

英文题名：Inhibition of homo-coupling of arylboronic acids in ligand free Pd(II)-catalyzed Suzuki reaction

作者：Tao, Xiao-Chun; Zhang, Yue-Ping; He, Tia-Xiong; Shen, Dong

机构：[1]E China Univ Sci & Technol, Organomet Chem Lab, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Phys Chem Lab, Shanghai 200237, Peoples R China

年份：2007

卷号：25

期号：9

起止页码：1326

外文期刊名：CHINESE JOURNAL OF CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000249473600020)，CCR-EXPANDED(收录号:WOS:000249473600020)】；

语种：英文

外文关键词：homo-coupling; cross-coupling; isopropanol; aryl bromide; arylboronic acid

摘要：A series of solvents were examined for the ligand free Pd(II)-catalyzed Suzuki reaction of 4-bromotoluene with phenylboronic acid. It was found that the PdCl2/i-PrOH system could efficiently inhibit the homo-coupling of phenylboronic acid and give a cross-coupling product in high yields. The substrates with a wide variety of functional groups were tolerated in the system. A possible mechanism for this system was proposed.