文献类型：期刊文献

英文题名：Toward High-Efficient Chiral Separation Using Hierarchically Porous HROP@Silica-Gel-Sheet Composite

作者：Chen, Tingting[1,2];Tan, Huiling[1,2];Chen, Qibin[1,2];Gu, Liangning[1,2];Wei, Zishuai[1,2];Liu, Honglai[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2019

卷号：11

期号：51

起止页码：48402

外文期刊名：ACS APPLIED MATERIALS & INTERFACES

收录：;EI(收录号：20195207939555);WOS:【SCI-EXPANDED(收录号:WOS:000505626900076)】；

基金：This work is supported by National Natural Science Foundation of China and the 111 Project of Ministry of Education of China. Qibin Chen received funding from National Natural Science Foundation of China (No. 21576079). Honglai Liu received funding from National Natural Science Foundation of China (No. 91834301) and the 111 Project of Ministry of Education of China (No. B08021).

语种：英文

外文关键词：hierarchical porosity; hyper-cross-linked polymer; composite; racemates; chiral separation

摘要：Separating racemates is still a great challenge for their similarity in chemical structures and physicochemical properties. Despite exhibiting a significant potential in the adsorption separation due to their intrinsic characteristics, hierarchically porous materials utilized in enantioseparation have rarely been reported to date. Furthermore, the molding of such materials together with their hybrid organic-inorganic monoliths is generally required to meet various prerequisites in diverse large-scale industrial applications, but without sacrificing their inherently hierarchical architectures. In this work, a three-dimensional hierarchically porous organic inorganic composite was simply and feasibly prepared via integrating the micro/mesoporous hyper-cross-linked resin organic polymer (HROP) with macroporous silica gel sheet (SGS), followed by a chiral selector postmodification, named as HROP@SGS. Racemic 1-phenylethanol, ibuprofen, and naproxen could be separated only using such a piece of HROP@SGS as the filler with a solid phase extraction technique. Herein, HROP@SGS exhibited extraordinary chiral resolution performances and succeeded in achieving a complete chiral resolution. Our findings suggest that this simple strategy proposed by us, that is, combining the chiral micro/mesoporous organic materials with macroporous inorganic substrates, can be employed to prepare an unprecedented enantioseparation material, which has a promising potential in large-scale industrial applications, such as fixed-bed and membrane separation.