文献类型：期刊文献

英文题名：Borondipyrromethene-derived Cu²⁺ sensing chemodosimeter for fast and selective detection

作者：Zhao, Chunchang[1];Feng, Peng;Cao, Jian;Wang, Xuzhe;Yang, Yang;Zhang, Yulin;Zhang, Jinxing;Zhang, Yanfen

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2012

卷号：10

期号：15

起止页码：3104

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000301958100027)】；

基金：We gratefully acknowledge the financial support by the National Science Foundation of China (grant no.: 20902021, 21002013), the Scientific Research Foundation for the Returned Overseas Chinese Scholars (State Education Ministry).

语种：英文

摘要：Here, we report a new Cu2+-selective fluorescent turn-on probe BODIPY-EP, in which the 2-pyridinecarboxylic acid is connected to a 6-hydroxyindole-based BODIPY platform through an ester linkage. The ester bond of BODIPY-EP is selectively hydrolyzed by the reaction with Cu2+ under mild and neutral conditions to generate BODIPY-OH, showing strong characteristic fluorescence of BODIPY-OH. The favorable features of BODIPY-EP towards Cu2+ include fast response, large fluorescence enhancement and high selectivity. We further demonstrated that the membrane-permeable probe reacts with intracellular Cu2+ and exhibits bright fluorescence in living cells.