文献类型：期刊文献

英文题名：A polyvinyl alcohol-functionalized sorbent for extraction and determination of aminoglycoside antibiotics in honey

作者：Wang, Yuan[1];Ji, Shunli[1];Zhang, Feng[2];Zhang, Feifang[1];Yang, Bingcheng[1];Liang, Xinmiao[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[2]Chinese Acad Inspect & Quarantine, Inst Food Safety, Beijing 100123, Peoples R China

年份：2015

卷号：1403

起止页码：32

外文期刊名：JOURNAL OF CHROMATOGRAPHY A

收录：;EI(收录号：20155101697129);WOS:【SCI-EXPANDED(收录号:WOS:000357232600003)】；

基金：The research was sponsored by National Natural Science Foundation of China (No. 21177040, 21477037).

语种：英文

外文关键词：Polyvinyl alcohol; HILIC; Aminoglycoside antibiotics; Sorbent; Honey

摘要：A novel highly hydrophilic sorbent simply prepared by coating polyvinyl alcohol (PVA) onto silica gel was used for extraction and determination of aminoglycoside antibiotics (AAs). The fabricated PVA coating is aimed to effectively protect core silica gel inside and offers good hydrophilic property. In combination of hydrophilic interaction chromatography tandem mass spectrometry, the performance of the sorbent was evaluated by selecting four model AAs (dihydrostreptomycin, streptomycin, kanamycin, spectinomycin). The sorbent was found to have effective adsorption ability to hydrophilic AAs, which was superior or comparable to those of commercial ones. Good recoveries (84-112%) of model AAs spiked in honey were obtained with good precision (<12.4%) and the limit of quantitation for the proposed method was in the range of 7.8-19.4 ng/mL. (C) 2015 Elsevier B.V. All rights reserved.