文献类型：期刊文献

英文题名：Direct defluorinative amidation-hydrolysis reaction of gem-difluoroalkenes with N,N-dimethylformamide, and primary and secondary amines

作者：Wang, Biyun[1];Zhao, Xianghu[1];Liu, Qingyun[1];Cao, Song[1]

机构：[1]ECUST, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2018

卷号：16

期号：44

起止页码：8546

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20184606081297);WOS:【SCI-EXPANDED(收录号:WOS:000450437500013)，CCR-EXPANDED(收录号:WOS:000450437500013)】；

基金：We are grateful for financial support from the National Natural Science Foundation of China (Grant No. 21472043 and 21272070).

语种：英文

外文关键词：Amines

摘要：A novel and efficient method for the synthesis of arylacetamides by the reactions of gem-difluoroalkenes with N,N-dialkylformamides, and primary and secondary amines with the assistance of KOtBu and water was developed.