文献类型：期刊文献

英文题名：DBN-Mediated Addition Reaction of α-(Trifluoromethyl)styrenes with Diazoles, Triazoles, Tetrazoles, and Primary, Secondary, and Secondary Cyclic Amines

作者：He, Jingjing[1];Liu, Chuan[1];Deng, Yupian[1];Zeng, Qianding[1];Zhang, Yi[1];Liu, Ying[1];Zheng, Pai[1];Cao, Song[1]

机构：[1]East China Univ Sci & Technol ECUST, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2022

卷号：24

期号：12

起止页码：2299

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000780673100006)，CCR-EXPANDED(收录号:WOS:000780673100006)】；

基金：The authors are grateful for financial support from the National Natural Science Foundation of China (Grant 21472043) .

语种：英文

摘要：A mild and efficient DBN-mediated addition reaction of alpha-(trifluoromethyl)styrenes with diazoles, triazoles, tetrazoles, and primary, secondary, and secondary cyclic amines was developed. This practical protocol provided a robust method for the synthesis of various beta-trifluoromethyl nitrogen-containing heterocycles and beta-trifluoromethyl amines.